人 MAPKAPK5 (NM_139078) cDNA克隆

基本信息

Accession: NM_139078
基因名称: MAPKAPK5
基因别名: MK5; MK-5; PRAK; MAPKAP-K5
基因描述: Homo sapiens mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1422 (查看编码区序列)
翻译后氨基酸长度: 473 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an extra 6 nt segment in the coding region when compared to variant 1. It encodes an isoform (2) longer by 2 aa, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G116788 人 MAPKAPK5 (NM_139078) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MAPKAPK5 (NM_003668) cDNA克隆 transcript variant 1
人 MAPKAPK5 (NM_139078) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]

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