人 KLK8 (NM_144507) cDNA克隆

基本信息

Accession: NM_144507
基因名称: KLK8
基因别名: NP; HNP; NRPN; PRSS19; TADG14
基因描述: Homo sapiens kallikrein-related peptidase 8 (KLK8), transcript variant 4, mRNA.
种属: Human
CDS区长度: 99 (查看编码区序列)
翻译后氨基酸长度: 32 (查看氨基酸序列)
Transcript Variant: This variant (4, also known as T4) lacks three exons in the coding region, which results in a frameshift and an early stop codon, compared to variant 2. The encoded isoform (4) is shorter and has a distinct C-terminus, compared to isoform 2. This variant is based on data in PMID: 11309326 and 20360129.

订购信息

产品编号 产品名称 载体 规格 价格
G116486 人 KLK8 (NM_144507) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 KLK8 (NM_007196) cDNA克隆 transcript variant 1
人 KLK8 (NM_144505) cDNA克隆 transcript variant 2
人 KLK8 (NM_144506) cDNA克隆 transcript variant 3
人 KLK8 (NM_144507) cDNA克隆 transcript variant 4
人 KLK8 (NM_001281431) cDNA克隆 transcript variant 5

基因简介

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

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