人 INTS6 (NM_001039938) cDNA克隆

Accession: NM_001039938
基因名称: INTS6
基因别名: HDB; INT6; DBI-1; DDX26; DICE1; DDX26A; Notchl2
基因描述: Homo sapiens integrator complex subunit 6 (INTS6), transcript variant 3, mRNA.
种属: Human
CDS区长度: 348 (查看编码区序列)
翻译后氨基酸长度: 115 (查看氨基酸序列)
Transcript Variant: This variant (3) is missing many 3' exons and contains an alternative segment at the 3' end compared to variant 1. This results in a shorter isoform (c) with a distinct C-terminus compared to isoform a.
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G116314 人 INTS6 (NM_001039938) cDNA克隆 pDONR223 2ug质粒 点击询价

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]