人 NOX4 (NM_001143837) cDNA克隆

基本信息

Accession: NM_001143837
基因名称: NOX4
基因别名: KOX; KOX-1; RENOX
基因描述: Homo sapiens NADPH oxidase 4 (NOX4), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1665 (查看编码区序列)
翻译后氨基酸长度: 554 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and coding region compared to variant 1. These differences cause translation initiation at a downstream AUG and result in a protein (isoform c) with a shorter N-terminus compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G116196 人 NOX4 (NM_001143837) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NOX4 (NM_016931) cDNA克隆 transcript variant 1
人 NOX4 (NM_001143836) cDNA克隆 transcript variant 2
人 NOX4 (NM_001143837) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]

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