ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008]
Accession: | NM_014882 |
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基因名称: | ARHGAP25 |
基因别名: | KAIA0053 |
基因描述: | Homo sapiens Rho GTPase activating protein 25 (ARHGAP25), transcript variant 2, mRNA. |
种属: | Human |
CDS区长度: | 1917 (查看编码区序列) |
翻译后氨基酸长度: | 638 (查看氨基酸序列) |
Transcript Variant: | This variant (2) differs in the 5' UTR and 5' coding region, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (b) is shorter and has a distinct N-terminus, compared to isoform a. |
人 ARHGAP25 (NM_001007231) cDNA克隆 | transcript variant 1 |
人 ARHGAP25 (NM_014882) cDNA克隆 | transcript variant 2 |
人 ARHGAP25 (NM_001166276) cDNA克隆 | transcript variant 3 |
人 ARHGAP25 (NM_001166277) cDNA克隆 | transcript variant 4 |
ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008]