NOP16 is transcriptionally regulated by c-Myc (MYC; MIM 190080), upregulated in breast cancer, and overexpression is associated with poor patient survival (Butt et al., 2008).[supplied by OMIM, Jun 2009]
Accession: | NM_001256540 |
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基因名称: | NOP16 |
基因别名: | HSPC111; HSPC185 |
基因描述: | Homo sapiens NOP16 nucleolar protein (NOP16), transcript variant 2, mRNA. |
种属: | Human |
CDS区长度: | 696 (查看编码区序列) |
翻译后氨基酸长度: | 231 (查看氨基酸序列) |
Transcript Variant: | This variant (2) uses an alternate in-frame splice junction at the 5' end of the last exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter by 1 aa compared to isoform 1. |
人 NOP16 (NM_001256539) cDNA克隆 | transcript variant 1 |
人 NOP16 (NM_001256540) cDNA克隆 | transcript variant 2 |
人 NOP16 (NM_016391) cDNA克隆 | transcript variant 3 |
NOP16 is transcriptionally regulated by c-Myc (MYC; MIM 190080), upregulated in breast cancer, and overexpression is associated with poor patient survival (Butt et al., 2008).[supplied by OMIM, Jun 2009]