人 PRRG1 (NM_001173486) cDNA克隆

基本信息

Accession: NM_001173486
基因名称: PRRG1
基因别名: PRGP1
基因描述: Homo sapiens proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1), transcript variant 5, mRNA.
种属: Human
CDS区长度: 249 (查看编码区序列)
翻译后氨基酸长度: 82 (查看氨基酸序列)
Transcript Variant: This variant (5) is missing a 5' non-coding exon, and contains an alternate 3' terminal exon compared to variant 1. The latter causes a frame-shift and a shorter isoform (2) with a distinct C-terminus compared to isoform 1. Isoform 2 retains a partial Gla domain at the N-terminus, however, this protein is predicted and lacks experimental evidence.

订购信息

产品编号 产品名称 载体 规格 价格
G115879 人 PRRG1 (NM_001173486) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PRRG1 (NM_000950) cDNA克隆 transcript variant 1
人 PRRG1 (NM_001142395) cDNA克隆 transcript variant 2
人 PRRG1 (NM_001173489) cDNA克隆 transcript variant 3
人 PRRG1 (NM_001173490) cDNA克隆 transcript variant 4
人 PRRG1 (NM_001173486) cDNA克隆 transcript variant 5

基因简介

This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]

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