人 TLE3 (NM_001282982) cDNA克隆

基本信息

Accession: NM_001282982
基因名称: TLE3
基因别名: ESG; ESG3; GRG3; HsT18976
基因描述: Homo sapiens transducin-like enhancer of split 3 (TLE3), transcript variant 7, mRNA.
种属: Human
CDS区长度: 2100 (查看编码区序列)
翻译后氨基酸长度: 699 (查看氨基酸序列)
Transcript Variant: This variant (7) represents the use of an alternate promoter and has multiple differences compared to variant 1. These differences result in a distinct 5' UTR and cause translation initiation at a downstream start codon compared to variant 1. The encoded isoform (g) is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G115829 人 TLE3 (NM_001282982) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TLE3 (NM_005078) cDNA克隆 transcript variant 1
人 TLE3 (NM_001105192) cDNA克隆 transcript variant 2
人 TLE3 (NM_020908) cDNA克隆 transcript variant 3
人 TLE3 (NM_001282980) cDNA克隆 transcript variant 4
人 TLE3 (NM_001282979) cDNA克隆 transcript variant 5
人 TLE3 (NM_001282981) cDNA克隆 transcript variant 6
人 TLE3 (NM_001282982) cDNA克隆 transcript variant 7

基因简介

This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]

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