This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq, Sep 2008]
Accession: | NM_001244710 |
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基因名称: | GFPT1 |
基因别名: | GFA; GFAT; GFPT; MSLG; GFAT1; CMSTA1; GFAT 1; GFAT1m; GFPT1L |
基因描述: | Homo sapiens glutamine--fructose-6-phosphate transaminase 1 (GFPT1), transcript variant 1, mRNA. |
种属: | Human |
CDS区长度: | 2100 (查看编码区序列) |
翻译后氨基酸长度: | 699 (查看氨基酸序列) |
Transcript Variant: | This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1). |
人 GFPT1 (NM_001244710) cDNA克隆 | transcript variant 1 |
人 GFPT1 (NM_002056) cDNA克隆 | transcript variant 2 |
This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq, Sep 2008]