人 MAP3K12 (NM_001193511) cDNA克隆

基本信息

Accession: NM_001193511
基因名称: MAP3K12
基因别名: DLK; MUK; ZPK; ZPKP1; MEKK12
基因描述: Homo sapiens mitogen-activated protein kinase kinase kinase 12 (MAP3K12), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2679 (查看编码区序列)
翻译后氨基酸长度: 892 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G115634 人 MAP3K12 (NM_001193511) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MAP3K12 (NM_001193511) cDNA克隆 transcript variant 1
人 MAP3K12 (NM_006301) cDNA克隆 transcript variant 2

基因简介

This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq, Jul 2010]

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