人 HERC3 (NM_001271602) cDNA克隆

Accession: NM_001271602
基因名称: HERC3
基因描述: Homo sapiens HECT and RLD domain containing E3 ubiquitin protein ligase 3 (HERC3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2799 (查看编码区序列)
翻译后氨基酸长度: 932 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate 5' exon and portion of the 5' coding region. These differences cause translation initiation at a downstream AUG and result in an isoform (2) which has a shorter N-terminus, compared to isoform 1.
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G115617 人 HERC3 (NM_001271602) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]