人 YAF2 (NM_001190980) cDNA克隆

基本信息

Accession: NM_001190980
基因名称: YAF2
基因描述: Homo sapiens YY1 associated factor 2 (YAF2), transcript variant 4, mRNA.
种属: Human
CDS区长度: 354 (查看编码区序列)
翻译后氨基酸长度: 117 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks several 3' exons, but has an alternate 3' exon, as compared to variant 1. The resulting isoform (4) is shorter and has a different C-terminus, as compared to isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G115426 人 YAF2 (NM_001190980) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 YAF2 (NM_001190979) cDNA克隆 transcript variant 1
人 YAF2 (NM_005748) cDNA克隆 transcript variant 2
人 YAF2 (NM_001190977) cDNA克隆 transcript variant 3
人 YAF2 (NM_001190980) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

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