This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
人 RNF41 (NM_005785) cDNA克隆
| Accession: | NM_005785 |
|---|---|
| 基因名称: | RNF41 |
| 基因别名: | FLRF; NRDP1; SBBI03 |
| 基因描述: | Homo sapiens ring finger protein 41 (RNF41), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 954 (查看编码区序列) |
| 翻译后氨基酸长度: | 317 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) encodes the longer isoform (1). Variants 1, 3 and 4 encode the same protein. |
| 人 RNF41 (NM_005785) cDNA克隆 | transcript variant 1 |
| 人 RNF41 (NM_194358) cDNA克隆 | transcript variant 2 |
| 人 RNF41 (NM_194359) cDNA克隆 | transcript variant 3 |
| 人 RNF41 (NM_001242826) cDNA克隆 | transcript variant 4 |
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