人 TRMT6 (NM_001281467) cDNA克隆

Accession: NM_001281467
基因名称: TRMT6
基因别名: GCD10; CGI-09; Gcd10p
基因描述: Homo sapiens tRNA methyltransferase 6 homolog (S. cerevisiae) (TRMT6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 984 (查看编码区序列)
翻译后氨基酸长度: 327 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in its 5' UTR and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1.
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G115048 人 TRMT6 (NM_001281467) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]