人 NCK2 (NM_001004722) cDNA克隆

基本信息

Accession: NM_001004722
基因名称: NCK2
基因别名: GRB4; NCKbeta
基因描述: Homo sapiens NCK adaptor protein 2 (NCK2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 252 (查看编码区序列)
翻译后氨基酸长度: 83 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an exon, which results in a frameshift, compared to variant 1. The resulting protein (isoform B) is shorter and has a distinct C-terminus, compared to isoform A.

订购信息

产品编号 产品名称 载体 规格 价格
G114960 人 NCK2 (NM_001004722) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NCK2 (NM_003581) cDNA克隆 transcript variant 1
人 NCK2 (NM_001004720) cDNA克隆 transcript variant 2
人 NCK2 (NM_001004722) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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