人 ECE2 (NM_001100121) cDNA克隆

基本信息

Accession: NM_001100121
基因名称: ECE2
基因描述: Homo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 5, mRNA.
种属: Human
CDS区长度: 2298 (查看编码区序列)
翻译后氨基酸长度: 765 (查看氨基酸序列)
Transcript Variant: This variant (5) differs in the 5' UTR and CDS compared to variant 1. The resulting isoform (E) has a distinct N-terminus compared to isoform A.

订购信息

产品编号 产品名称 载体 规格 价格
G114727 人 ECE2 (NM_001100121) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ECE2 (NM_014693) cDNA克隆 transcript variant 1
人 ECE2 (NM_001037324) cDNA克隆 transcript variant 2
人 ECE2 (NM_032331) cDNA克隆 transcript variant 3
人 ECE2 (NM_001100120) cDNA克隆 transcript variant 4
人 ECE2 (NM_001100121) cDNA克隆 transcript variant 5

基因简介

This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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