人 NUMB (NM_003744) cDNA克隆

基本信息

Accession: NM_003744
基因名称: NUMB
基因别名: S171; C14orf41; c14_5527
基因描述: Homo sapiens numb homolog (Drosophila) (NUMB), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1923 (查看编码区序列)
翻译后氨基酸长度: 640 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G114569 人 NUMB (NM_003744) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NUMB (NM_001005743) cDNA克隆 transcript variant 1
人 NUMB (NM_001005744) cDNA克隆 transcript variant 2
人 NUMB (NM_003744) cDNA克隆 transcript variant 3
人 NUMB (NM_001005745) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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