人 POLD4 (NM_001256870) cDNA克隆

Accession: NM_001256870
基因名称: POLD4
基因别名: p12; POLDS
基因描述: Homo sapiens polymerase (DNA-directed), delta 4, accessory subunit (POLD4), transcript variant 2, mRNA.
种属: Human
CDS区长度: 240 (查看编码区序列)
翻译后氨基酸长度: 79 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
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G114306 人 POLD4 (NM_001256870) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]