人 ELAC2 (NM_018127) cDNA克隆

基本信息

Accession: NM_018127
基因名称: ELAC2
基因别名: ELC2; HPC2; COXPD17
基因描述: Homo sapiens elaC ribonuclease Z 2 (ELAC2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2481 (查看编码区序列)
翻译后氨基酸长度: 826 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G114251 人 ELAC2 (NM_018127) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ELAC2 (NM_018127) cDNA克隆 transcript variant 1
人 ELAC2 (NM_173717) cDNA克隆 transcript variant 2
人 ELAC2 (NM_001165962) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

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