人 PLCG2 (NM_002661) cDNA克隆

Accession: NM_002661
基因名称: PLCG2
基因别名: FCAS3; APLAID
基因描述: Homo sapiens phospholipase C, gamma 2 (phosphatidylinositol-specific) (PLCG2), mRNA.
种属: Human
CDS区长度: 3798 (查看编码区序列)
翻译后氨基酸长度: 1265 (查看氨基酸序列)
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G114216 人 PLCG2 (NM_002661) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011]