人 RASAL1 (NM_004658) cDNA克隆

基本信息

Accession: NM_004658
基因名称: RASAL1
基因别名: RASAL
基因描述: Homo sapiens RAS protein activator like 1 (GAP1 like) (RASAL1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2415 (查看编码区序列)
翻译后氨基酸长度: 804 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and uses two alternate, in-frame splice sites in the coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G114162 人 RASAL1 (NM_004658) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RASAL1 (NM_001193520) cDNA克隆 transcript variant 1
人 RASAL1 (NM_004658) cDNA克隆 transcript variant 2
人 RASAL1 (NM_001193521) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010]

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