人 BUB1 (NM_001278616) cDNA克隆

基本信息

Accession: NM_001278616
基因名称: BUB1
基因别名: BUB1A; BUB1L; hBUB1
基因描述: Homo sapiens BUB1 mitotic checkpoint serine/threonine kinase (BUB1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3198 (查看编码区序列)
翻译后氨基酸长度: 1065 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G114097 人 BUB1 (NM_001278616) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 BUB1 (NM_004336) cDNA克隆 transcript variant 1
人 BUB1 (NM_001278616) cDNA克隆 transcript variant 2
人 BUB1 (NM_001278617) cDNA克隆 transcript variant 3

基因简介

This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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