人 NLRP12 (NM_001277126) cDNA克隆

基本信息

Accession: NM_001277126
基因名称: NLRP12
基因别名: RNO; PAN6; RNO2; FCAS2; NALP12; PYPAF7; CLR19.3
基因描述: Homo sapiens NLR family, pyrin domain containing 12 (NLRP12), transcript variant 3, mRNA.
种属: Human
CDS区长度: 3189 (查看编码区序列)
翻译后氨基酸长度: 1062 (查看氨基酸序列)
Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).

订购信息

产品编号 产品名称 载体 规格 价格
G114064 人 NLRP12 (NM_001277126) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NLRP12 (NM_144687) cDNA克隆 transcript variant 2
人 NLRP12 (NM_001277126) cDNA克隆 transcript variant 3
人 NLRP12 (NM_001277129) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

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