人 PAM (NM_138766) cDNA克隆

基本信息

Accession: NM_138766
基因名称: PAM
基因别名: PAL; PHM
基因描述: Homo sapiens peptidylglycine alpha-amidating monooxygenase (PAM), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2718 (查看编码区序列)
翻译后氨基酸长度: 905 (查看氨基酸序列)
Transcript Variant: This variant (2), also known as PAM-15, lacks an exon of 204 nucleotides and uses an alternate splice site in the coding region compared to variant 1. The transcript maintains the same reading frame but the encoded isoform b lacks 69 internal amino acids compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G113960 人 PAM (NM_138766) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PAM (NM_000919) cDNA克隆 transcript variant 1
人 PAM (NM_138766) cDNA克隆 transcript variant 2
人 PAM (NM_138821) cDNA克隆 transcript variant 3
人 PAM (NM_138822) cDNA克隆 transcript variant 4
人 PAM (NM_001177306) cDNA克隆 transcript variant 5

基因简介

This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq, Jul 2008]

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