人 PLS3 (NM_001282338) cDNA克隆

Accession: NM_001282338
基因名称: PLS3
基因别名: BMND18; T-plastin
基因描述: Homo sapiens plastin 3 (PLS3), transcript variant 5, mRNA.
种属: Human
CDS区长度: 1758 (查看编码区序列)
翻译后氨基酸长度: 585 (查看氨基酸序列)
Transcript Variant: This variant (5) contains an alternate 5' non-coding exon and a novel exon in the 5' region that results in translation initiation from an in-frame downstream start codon compared to variant 1. The encoded isoform (4) has a shorter N-terminus compared to isoform 1.
产品编号 产品名称 载体 规格 价格
G113746 人 PLS3 (NM_001282338) cDNA克隆 pDONR223 2ug质粒 点击询价

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]