人 PDLIM5 (NM_001256427) cDNA克隆

Accession: NM_001256427
基因名称: PDLIM5
基因别名: L9; ENH; LIM; ENH1
基因描述: Homo sapiens PDZ and LIM domain 5 (PDLIM5), transcript variant 7, mRNA.
种属: Human
CDS区长度: 1452 (查看编码区序列)
翻译后氨基酸长度: 483 (查看氨基酸序列)
Transcript Variant: This variant (7) uses an alternate in-frame splice site in the 5' coding region, contains an additional in-frame exon in the central coding region, and uses alternate 3' exon structure and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (g) has a distinct C-terminus and is shorter than isoform a.
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G113733 人 PDLIM5 (NM_001256427) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]