人 VPS45 (NM_001279353) cDNA克隆

基本信息

Accession: NM_001279353
基因名称: VPS45
基因别名: H1; SCN5; VSP45; VPS45A; VPS45B; VPS54A; VSP45A; H1VPS45
基因描述: Homo sapiens vacuolar protein sorting 45 homolog (S. cerevisiae) (VPS45), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1617 (查看编码区序列)
翻译后氨基酸长度: 538 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and has multiple differences in the coding region, compared to variant 1. The resulting isoform (2) is shorter and has a shorter N-terminus, lacks an internal segment and has a longer and distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G113656 人 VPS45 (NM_001279353) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 VPS45 (NM_007259) cDNA克隆 transcript variant 1
人 VPS45 (NM_001279353) cDNA克隆 transcript variant 2
人 VPS45 (NM_001279354) cDNA克隆 transcript variant 3
人 VPS45 (NM_001279355) cDNA克隆 transcript variant 4

基因简介

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]

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