人 DTNB (NM_183361) cDNA克隆

基本信息

Accession: NM_183361
基因名称: DTNB
基因描述: Homo sapiens dystrobrevin, beta (DTNB), transcript variant 5, mRNA.
种属: Human
CDS区长度: 1683 (查看编码区序列)
翻译后氨基酸长度: 560 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks three in-frame exons in the 3' coding region, compared to variant 1. The resulting isoform (5) lacks three internal segments, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G113630 人 DTNB (NM_183361) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 DTNB (NM_021907) cDNA克隆 transcript variant 1
人 DTNB (NM_033147) cDNA克隆 transcript variant 2
人 DTNB (NM_033148) cDNA克隆 transcript variant 3
人 DTNB (NM_183360) cDNA克隆 transcript variant 4
人 DTNB (NM_183361) cDNA克隆 transcript variant 5
人 DTNB (NM_001256303) cDNA克隆 transcript variant 6
人 DTNB (NM_001256304) cDNA克隆 transcript variant 7
人 DTNB (NM_001256308) cDNA克隆 transcript variant 8

基因简介

This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

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