人 EZH2 (NM_001203248) cDNA克隆

Accession: NM_001203248
基因名称: EZH2
基因别名: WVS; ENX1; EZH1; KMT6; WVS2; ENX-1; EZH2b; KMT6A
基因描述: Homo sapiens enhancer of zeste homolog 2 (Drosophila) (EZH2), transcript variant 4, mRNA.
种属: Human
CDS区长度: 2214 (查看编码区序列)
翻译后氨基酸长度: 737 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks two in-frame segments in the coding region, as compared to variant 1. The resulting isoform (d) lacks two internal segments, as compared to isoform a.
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G112793 人 EZH2 (NM_001203248) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]