人 LNX1 (NM_032622) cDNA克隆

基本信息

Accession: NM_032622
基因名称: LNX1
基因别名: LNX; MPDZ; PDZRN2
基因描述: Homo sapiens ligand of numb-protein X 1, E3 ubiquitin protein ligase (LNX1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1899 (查看编码区序列)
翻译后氨基酸长度: 632 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (b, also known as LNXp70) contains a distinct N-terminus and is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G112743 人 LNX1 (NM_032622) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 LNX1 (NM_001126328) cDNA克隆 transcript variant 1
人 LNX1 (NM_032622) cDNA克隆 transcript variant 2

基因简介

This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene. [provided by RefSeq, Jul 2008]

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