人 RLIM (NM_016120) cDNA克隆

Accession: NM_016120
基因名称: RLIM
基因别名: RNF12; NY-REN-43
基因描述: Homo sapiens ring finger protein, LIM domain interacting (RLIM), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1875 (查看编码区序列)
翻译后氨基酸长度: 624 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks an alternate exon in the 5' UTR, compared to variant 2, and may represent the more abundant form. Both variants encode the same protein.
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G112485 人 RLIM (NM_016120) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2009]