人 MBD4 (NM_001276271) cDNA克隆

基本信息

Accession: NM_001276271
基因名称: MBD4
基因别名: MED1
基因描述: Homo sapiens methyl-CpG binding domain protein 4 (MBD4), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1719 (查看编码区序列)
翻译后氨基酸长度: 572 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an exon and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR compared to variant 1. It encodes isoform 3 which is shorter and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G112332 人 MBD4 (NM_001276271) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MBD4 (NM_003925) cDNA克隆 transcript variant 1
人 MBD4 (NM_001276270) cDNA克隆 transcript variant 2
人 MBD4 (NM_001276271) cDNA克隆 transcript variant 3
人 MBD4 (NM_001276272) cDNA克隆 transcript variant 4
人 MBD4 (NM_001276273) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]

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