人 HABP2 (NM_001177660) cDNA克隆

Accession: NM_001177660
基因名称: HABP2
基因别名: FSAP; HABP; PHBP; HGFAL
基因描述: Homo sapiens hyaluronan binding protein 2 (HABP2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1605 (查看编码区序列)
翻译后氨基酸长度: 534 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
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G112273 人 HABP2 (NM_001177660) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]