人 DGCR2 (NM_001173534) cDNA克隆

基本信息

Accession: NM_001173534
基因名称: DGCR2
基因别名: IDD; LAN; DGS-C; SEZ-12
基因描述: Homo sapiens DiGeorge syndrome critical region gene 2 (DGCR2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1521 (查看编码区序列)
翻译后氨基酸长度: 506 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The resulting isoform (3) lacks two internal segments, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G112198 人 DGCR2 (NM_001173534) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 DGCR2 (NM_005137) cDNA克隆 transcript variant 1
人 DGCR2 (NM_001173533) cDNA克隆 transcript variant 2
人 DGCR2 (NM_001173534) cDNA克隆 transcript variant 3
人 DGCR2 (NM_001184781) cDNA克隆 transcript variant 4

基因简介

Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

相关产品