人 SP110 (NM_004510) cDNA克隆

Accession: NM_004510
基因名称: SP110
基因别名: IPR1; VODI; IFI41; IFI75
基因描述: Homo sapiens SP110 nuclear body protein (SP110), transcript variant b, mRNA.
种属: Human
CDS区长度: 1650 (查看编码区序列)
翻译后氨基酸长度: 549 (查看氨基酸序列)
Transcript Variant: This variant (b) uses an alternate exon for the 3' coding region and 3' UTR, as compared to variant c. The encoded protein (isoform b) has a shorter and distinct C-terminus and lacks the bromodomain when it is compared to isoform c.
产品编号 产品名称 载体 规格 价格
G112186 人 SP110 (NM_004510) cDNA克隆 pDONR223 2ug质粒 点击询价

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]