人 ZBTB7B (NM_001256455) cDNA克隆

Accession: NM_001256455
基因名称: ZBTB7B
基因别名: THPOK; ZFP67; ZBTB15; ZFP-67; c-KROX; hcKROX; ZNF857B
基因描述: Homo sapiens zinc finger and BTB domain containing 7B (ZBTB7B), transcript variant 5, mRNA.
种属: Human
CDS区长度: 1620 (查看编码区序列)
翻译后氨基酸长度: 539 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks two alternate exons in the 5' UTR and 5' coding region, and uses a downstream in-frame start codon, comapred to variant 3. The encoded isoform (1) is shorter at the N-terminus, compared to isoform 2.
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G112154 人 ZBTB7B (NM_001256455) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]