人 PDE1B (NM_000924) cDNA克隆

Accession: NM_000924
基因名称: PDE1B
基因别名: PDE1B1; PDES1B
基因描述: Homo sapiens phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1611 (查看编码区序列)
翻译后氨基酸长度: 536 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (1).
产品编号 产品名称 载体 规格 价格
G112112 人 PDE1B (NM_000924) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]