人 PARP3 (NM_005485) cDNA克隆

Accession: NM_005485
基因名称: PARP3
基因别名: IRT1; ARTD3; ADPRT3; ADPRTL2; ADPRTL3; PADPRT-3
基因描述: Homo sapiens poly (ADP-ribose) polymerase family, member 3 (PARP3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1602 (查看编码区序列)
翻译后氨基酸长度: 533 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and uses a downstream translational start codon, compared to variant 1. The resulting isoform (b) is shorter at the N-terminus, compared to isoform a.
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G112081 人 PARP3 (NM_005485) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]