人 RORA (NM_134262) cDNA克隆

Accession: NM_134262
基因名称: RORA
基因别名: ROR1; ROR2; ROR3; RZRA; NR1F1; RZR-ALPHA
基因描述: Homo sapiens RAR-related orphan receptor A (RORA), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1407 (查看编码区序列)
翻译后氨基酸长度: 468 (查看氨基酸序列)
Transcript Variant: This variant (4), also called RZR-alpha, contains a different 5' sequence as compared to variant 1. As a result, variant 4 encodes isoform d, whose 11 N-terminal aa differ from the 66 N-terminal aa of isoform a encoded by variant 1.
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G112003 人 RORA (NM_134262) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]