人 DOCK8 (NM_001193536) cDNA克隆

基本信息

Accession: NM_001193536
基因名称: DOCK8
基因别名: MRD2; ZIR8
基因描述: Homo sapiens dedicator of cytokinesis 8 (DOCK8), transcript variant 3, mRNA.
种属: Human
CDS区长度: 6096 (查看编码区序列)
翻译后氨基酸长度: 2031 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G111940 人 DOCK8 (NM_001193536) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 DOCK8 (NM_203447) cDNA克隆 transcript variant 1
人 DOCK8 (NM_001190458) cDNA克隆 transcript variant 2
人 DOCK8 (NM_001193536) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]

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