人 P4HTM (NM_177938) cDNA克隆

Accession: NM_177938
基因名称: P4HTM
基因别名: PH4; PH-4; PHD4; EGLN4; HIFPH4; P4H-TM
基因描述: Homo sapiens prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) (P4HTM), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1692 (查看编码区序列)
翻译后氨基酸长度: 563 (查看氨基酸序列)
Transcript Variant: This variant (3) contains two additional segments in the coding region, compared to variant 1. The resulting isoform (c) is longer, compared to isoform a.
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G111783 人 P4HTM (NM_177938) cDNA克隆 pDONR223 2ug质粒 点击询价

The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]