人 DNAJA3 (NM_001286516) cDNA克隆

Accession: NM_001286516
基因名称: DNAJA3
基因别名: TID1; HCA57; hTID-1
基因描述: Homo sapiens DnaJ (Hsp40) homolog, subfamily A, member 3 (DNAJA3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 903 (查看编码区序列)
翻译后氨基酸长度: 300 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks a segment in the 5' end and an alternate exon in the 3' end compared to variant 1. The resulting isoform (3) has shorter and distinct N- and C-termini compared to isoform 1.
产品编号 产品名称 载体 规格 价格
G111535 人 DNAJA3 (NM_001286516) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the DNAJ/Hsp40 protein family. DNAJ/Hsp40 proteins stimulate the ATPase activity of Hsp70 chaperones and play critical roles in protein folding, degradation, and multimeric complex assembly. The encoded protein is localized to mitochondria and mediates several cellular processes including proliferation, survival and apoptotic signal transduction. The encoded protein also plays a critical role in tumor suppression through interactions with oncogenic proteins including ErbB2 and the p53 tumor suppressor protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]