人 PPARG (NM_015869) cDNA克隆

Accession: NM_015869
基因名称: PPARG
基因别名: GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma
基因描述: Homo sapiens peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1518 (查看编码区序列)
翻译后氨基酸长度: 505 (查看氨基酸序列)
Transcript Variant: This variant (2) encodes the longer isoform (2).
产品编号 产品名称 载体 规格 价格
G111465 人 PPARG (NM_015869) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]