人 ARHGEF25 (NM_001111270) cDNA克隆

基本信息

Accession: NM_001111270
基因名称: ARHGEF25
基因别名: GEFT; p63RhoGEF
基因描述: Homo sapiens Rho guanine nucleotide exchange factor (GEF) 25 (ARHGEF25), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1860 (查看编码区序列)
翻译后氨基酸长度: 619 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, and in the presence and absence of exons in the 5' coding region, compared to variant 1. The resulting isoform (3) contains a distinct N-terminus and is longer than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G111430 人 ARHGEF25 (NM_001111270) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ARHGEF25 (NM_182947) cDNA克隆 transcript variant 1
人 ARHGEF25 (NM_001111270) cDNA克隆 transcript variant 3

基因简介

Rho GTPases alternate between an inactive GDP-bound state and an active GTP-bound state, and GEFs facilitate GDP/GTP exchange. This gene encodes a guanine nucleotide exchange factor (GEF) which interacts with Rho GTPases involved in contraction of vascular smooth muscles, regulation of responses to angiotensin II and lens cell differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

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