人 IRF3 (NM_001197123) cDNA克隆

Accession: NM_001197123
基因名称: IRF3
基因描述: Homo sapiens interferon regulatory factor 3 (IRF3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1179 (查看编码区序列)
翻译后氨基酸长度: 392 (查看氨基酸序列)
Transcript Variant: This variant (3, also known as IRF3a) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1.
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G111200 人 IRF3 (NM_001197123) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]