人 ILK (NM_001278442) cDNA克隆

基本信息

Accession: NM_001278442
基因名称: ILK
基因别名: P59; ILK-1; ILK-2; p59ILK
基因描述: Homo sapiens integrin-linked kinase (ILK), transcript variant 5, mRNA.
种属: Human
CDS区长度: 957 (查看编码区序列)
翻译后氨基酸长度: 318 (查看氨基酸序列)
Transcript Variant: This variant (5) uses an alternate splice site in the 5' UTR, lacks an exon in the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G111196 人 ILK (NM_001278442) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ILK (NM_004517) cDNA克隆 transcript variant 1
人 ILK (NM_001014794) cDNA克隆 transcript variant 2
人 ILK (NM_001014795) cDNA克隆 transcript variant 3
人 ILK (NM_001278441) cDNA克隆 transcript variant 4
人 ILK (NM_001278442) cDNA克隆 transcript variant 5

基因简介

This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

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