人 WIPI2 (NM_001278299) cDNA克隆

Accession: NM_001278299
基因名称: WIPI2
基因别名: Atg21; ATG18B; CGI-50; WIPI-2
基因描述: Homo sapiens WD repeat domain, phosphoinositide interacting 2 (WIPI2), transcript variant 6, mRNA.
种属: Human
CDS区长度: 933 (查看编码区序列)
翻译后氨基酸长度: 310 (查看氨基酸序列)
Transcript Variant: This variant (6) uses an alternate splice junction in a 5' exon compared to variant 1. This difference causes translation initiation at a downstream AUG and results in an isoform (f) with a shorter N-terminus, compared to isoform a.
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G111019 人 WIPI2 (NM_001278299) cDNA克隆 pDONR223 2ug质粒 点击询价

WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]