人 GSDMB (NM_001042471) cDNA克隆

Accession: NM_001042471
基因名称: GSDMB
基因别名: GSDML; PP4052; PRO2521
基因描述: Homo sapiens gasdermin B (GSDMB), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1212 (查看编码区序列)
翻译后氨基酸长度: 403 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks an alternate in-frame exon in the central coding region, compared to variant 3. The resulting isoform (1) lacks an internal segment, compared to isoform 3.
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G110770 人 GSDMB (NM_001042471) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Sep 2009]