人 ZFP36L1 (NM_004926) cDNA克隆

Accession: NM_004926
基因名称: ZFP36L1
基因别名: BRF1; ERF1; cMG1; ERF-1; Berg36; TIS11B; RNF162B
基因描述: Homo sapiens ZFP36 ring finger protein-like 1 (ZFP36L1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1017 (查看编码区序列)
翻译后氨基酸长度: 338 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1. Variants 1 and 2 encode the same isoform.
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G109941 人 ZFP36L1 (NM_004926) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]