人 ARHGEF26 (NM_001251963) cDNA克隆

基本信息

Accession: NM_001251963
基因名称: ARHGEF26
基因别名: SGEF; CSGEF; HMFN1864
基因描述: Homo sapiens Rho guanine nucleotide exchange factor (GEF) 26 (ARHGEF26), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2376 (查看编码区序列)
翻译后氨基酸长度: 791 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G109335 人 ARHGEF26 (NM_001251963) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ARHGEF26 (NM_001251962) cDNA克隆 transcript variant 1
人 ARHGEF26 (NM_015595) cDNA克隆 transcript variant 2
人 ARHGEF26 (NM_001251963) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

相关产品